ブックタイトル2013ATCC

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2013ATCC

ATCCHorizonEGFR (ΔE746-A750/+);PIK3CA (H1047R/+)EGFR (ΔE746-A750/+);PIK3CA (H1047R/+)遺伝子名カタログNo.細胞株名組織関連商品(+/H1047R) HTB-19 BT-20 Breast TCP-1003、30-4500K(+/H1047R) HTB-77 SK-OV-3 Ovary TCP-1021(+/H1047R) HTB-131 MDA-MB-453 Breast(+/H1047R) HTB-133 T-47D Breast 30-4500K遺伝子名カタログNo.親株名組織特記事項HD 200-001 hTERT-HME1 BreastHD 201-001 MCF10A BreastTCP-1002、TCP-1003、30-4500KDouble heterozygous knock-in of EGFR and PIK3CAactivating mutationsDouble heterozygous knock-in of EGFR and PIK3CAactivating mutationsATCC・Horizon Discovery遺伝子変異細胞株カタログ123456789KRAS (G12V/+); PIK3CA (E545K/+)HD 201-002MCF10ABreastKRAS (G13D/+); PIK3CA (H1047R/+)HD 200-003hTERT-HME1BreastPIK3CA (+/-)HD 105-001DLD-1ColonPIK3CA (+/-)HD 104-007HCT116ColonPIK3CA (E542K/+)HD 103-016SW48ColonPIK3CA (E545K/-)HD 105-012DLD-1ColonPIK3CA (E545K/+)HD 100-003hTERT-HME1BreastPIK3CA (E545K/+)HD 101-002MCF10ABreastPIK3CA (E545K/+)HD 103-001SW48ColonPIK3CA (H1047R/-)HD 104-012HCT116ColonPIK3CA (H1047R/+)HD 100-002hTERT-HME1BreastPIK3CA (H1047R/+)HD 101-011MCF10ABreastPIK3CA (H1047R/+)HD 103-005SW48ColonPIK3CA (H1047R/+)HD 107-003VACO 432ColonPIK3CA (H1047R/+); KRAS (G12V/+)HD 201-003MCF10ABreastPIK3CA (H1047R/+/+/+)HD 127-001WiDrColonTP53 (-/-); PIK3CA (H1047R/+)HD 101-043MCF10ABreastDouble heterozygous knock-in of KRAS and PIK3CAactivating mutationsDouble heterozygous knock-in of KRAS and PIK3CAactivating mutationsKnock-out of PIK3CA helix domain mutant allele(E545K) in heterozygous parental cellsKnock-out of PIK3CA kinase domain mutant allele(H1047R) in heterozygous parental cellsHeterozygous knock-in of PIK3CA helix domainactivating mutationKnock-out of PIK3CA wild type allele in heterozygousparental cellsHeterozygous knock-in of PIK3CA helix domainactivating mutationHeterozygous knock-in of PIK3CA helix domainactivating mutationHeterozygous knock-in of PIK3CA helix domainactivating mutationKnock-out of PIK3CA wild type allele in heterozygousparental cellsHeterozygous knock-in of PIK3CA kinase domainactivating mutationHeterozygous knock-in of PIK3CA kinase domainactivating mutationHeterozygous knock-in of PIK3CA kinase domainactivating mutationHeterozygous knock-in of PIK3CA kinase domainactivating mutationDouble heterozygous knock-in of KRAS and PIK3CAactivating mutationsHeterozygous knock-in of PIK3CA kinase domainactivating mutationHeterozygous knock-in of PIK3CA kinase domainactivating mutation in TP53 (-/-) parental cell lineAPCBRAFCDKN2ACTNNB1EGFRPIK3CAPIK3R1PTENRASRB1SMAD4TP5323