ブックタイトル2013ATCC

概要

2013ATCC

B-Raf (BRAF)遺伝子名カタログNo.親株名組織特記事項BRAF (-/-) HD R00-004 DLD-1 Colon Homozygous knock-out of BRAFBRAF (-/-) HD R02-012 HCT116 Colon Homozygous knock-out of BRAFBRAF (+/-/-) HD 106-003 RKO ColonKnock-out of both mutant BRAF alleles (V600E) intriploid parental cellsBRAF (V600E/-) HD 107-002 VACO 432 Colon Heterozygous knock-out of wild type BRAFBRAF (V600E/-/-) HD 106-004 RKO ColonBRAF (V600E/+) HD 104-048 HCT116 ColonBRAF (V600E/+) HD 100-005 hTERT-HME1 BreastBRAF (V600E/+) HD 101-012 MCF10A BreastKnock-out of wild type allele and one mutant BRAFallele (V600E) in triploid parental cellsHeterozygous knock-in of BRAF activating mutation(V600E)Heterozygous knock-in of BRAF activating mutation(V600E)Heterozygous knock-in of BRAF activating mutation(V600E)Horizon Discovery全細胞株リスト123456789BRAF (V600E/+) HD 101-026 MCF10A BreastBRAF (V600E/+);EGFR (ΔE746-A750/+)HD 200-002 hTERT-HME1 BreastBRAF (V600E/+/-) HD R05-012 RKO ColonHeterozygous knock-in of BRAF activating mutation(V600E)Double heterozygous knock-in of BRAF and EGFRactivating mutationsKnock-out of single mutant BRAF allele (V600E) intriploid parental cellsAvailableIsogenic Cell LinesBRAF (V600E/+/+) HD 103-003 SW48 ColonHeterozygous knock-in of BRAF activating mutation(V600E)BRAF (V600G/+) HD 104-066 HCT116 Colon Heterozygous knock-in of BRAF mutation (V600G)BRAF (V600K/+) HD 104-022 HCT116 ColonBRAF (V600K/+) HD 101-015 MCF10A BreastHeterozygous knock-in of BRAF activating mutation(V600R)Heterozygous knock-in of BRAF activating mutation(V600R)BRAF (V600M/+) HD 104-067 HCT116 Colon Heterozygous knock-in of BRAF mutation (V600M)BRAF (V600M/+) HD 104-067 HCT116 Colon Heterozygous knock-in of BRAF mutation (V600M)BRAF (V600R/+) HD 104-037 HCT116 ColonHeterozygous knock-in of BRAF activating mutation(V600R)BRAF (V600A/+) HD 104-075 HCT116 Colon Heterozygous knock-in of BRAF mutation (V600A)BRAF (V600E/+); TP53 (-/-) HD 101-024 MCF10A BreastBRAF (V600K/+); TP53 (-/-) HD 101-025 MCF10A BreastBAXHomozygous knock-out of TP53; heterozygousknockin of BRAF activating mutation (V600E)Homozygous knock-out of TP53; heterozygousknockin of BRAF activating mutation (V600K)BAX (-/-) HD R02-008 HCT116 Colon Homozygous knock-out of BAXBAX (-/-); CDKN1A (-/-) HD R02-010 HCT116 Colon Double homozygous knock-out of BAX and CDKN1ABLMBLM (-/-) HD R02-011 HCT116 Colon Homozygous knock-out of BLMIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsBRCA1BRCA1 (185delAG/+) HD 119-001 hTERT-IMECs BreastBRCA1 (185delAG/+) HD 101-018 MCF10A BreastHeterozygous knock-out of BRCA1 by knock-in ofpremature stop codon (AG185del)Heterozygous knock-in of 2-bp deletion in BRCA1resulting in a premature termination codon atposition 39AvailableX-MAN ? HaloTag RReporter Kits47