ブックタイトル2013ATCC

概要

2013ATCC

123456789Horizon Discovery全細胞株リストBRCA2遺伝子名カタログNo.親株名組織特記事項BRCA2 (-/-) HD 105-007 DLD-1 Colon Homozygous knock-out of BRCA2BRCA2 (+/-) HD 105-027 DLD-1 Colon Heterozygous knock-out of BRCA2BRCA2 (S3291E/-) HD 105-009 DLD-1 ColonBRCA2 (Y3308X/-) HD 105-008 DLD-1 ColonCCR5CCR5 (+/-) HD R10-002 hTERT RPE-1 RetinapigmentepitheliumCDC4 (FBXW7)FBXW7 (-/-) HD R00-005 DLD-1 ColonHeterozygous knock-in of BRCA2 hypomorphic pointmutation and knock-out of wild type alleleHeterozygous knock-in of BRCA2 inactivating pointmutation and knock-out of wild type alleleHeterozygous knock-out of CCR5Homozygous knock-out of FBXW7 exon 5 whichencodes F-box domain of the proteinAvailableIsogenic Cell LinesFBXW7 (-/-) HD R02-013 HCT116 ColonFBXW7 (+/-) HD R00-006 DLD-1 ColonCDK2Homozygous knock-out of FBXW7 exon 5 whichencodes F-box domain of the proteinHeterozygous knock-out of FBXW7 exon 5 whichencodes F-box domain of the proteinCDK2 (-/-) HD R02-015 HCT116 Colon Homozygous knock-out of CDK2In DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsAvailableX-MAN ? HaloTag RReporter KitsCDK2 (-/-); TP53 (-/-) HD R02-016 HCT116 Colon Double homozygous knock-out of CDK2 and TP53CHK1 (CHEK1)CHEK1 (+/-); TP53 (+/+) HD R02-077 HCT116 ColonCHEK1 (+/-); TP53 (+/sil) HD R00-026 DLD-1 ColonCHEK1 (+/-); TP53 (-/-) HD R02-078 HCT116 ColonCHEK1 (S317A/-); TP53 (S241F/sil) HD R00-007 DLD-1 ColonCHK2 (CHEK2)CHEK2 (-/-); TP53 (-/-) HD R02-018 HCT116 ColonCHEK2 (-/-); TP53 (+/+) HD R02-017 HCT116 ColonDEC1 (BHLHE40)Heterozygous knock-out of CHEK1; TP53 wild typebackgroundHeterozygous knock-out of CHEK1; knock-in of wildtype TP53Heterozygous knock-out of CHEK1; TP53 nullbackgroundHeterozygous knock-in of phosphorylation sitemutant and knock-out of wild type CHEK1; TP53(S241F) mutant backgroundHomozygous knock-out of CHEK2; TP53 nullbackgroundHomozygous knock-out of CHEK2; TP53 wild typebackgroundBHLHE40 (-/-) HD R01-001 HACAT Skin Heterozygous knock-out of BHLHE40Dicer (DICER1)DICER1 (-/-) HD R02-019 HCT116 ColonDICER1 (-/-) HD R05-001 RKO ColonDICER1 (-/-) HD R00-009 DLD-1 ColonDNA-PKcs (PRKDC)Homozygous disruption of DICER1 exon 5 helicasedomainHomozygous disruption of DICER1 exon 5 helicasedomainHomozygous disruption of DICER1 exon 5 helicasedomainPRKDC (-/-) HD R02-049 HCT116 Colon Homozygous knock-out of PRKDC48