ブックタイトル2013ATCC
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概要
2013ATCC
遺伝子名カタログNo.親株名組織特記事項FANCG (+/-) HD R05-002 RKO Colon Heterozygous knock-out of FANCGFBXW7FBXW7 (-/-) HD R02-013 HCT116 ColonFGFR2FGFR2 (S252W/+/+) HD 104-030 HCT116 ColonFGFR3FGFR3 (S249C/+) HD 104-044 HCT116 ColonFLT3FLT3 (D835Y/+) HD 104-041 HCT116 ColonHomozygous knock-out of FBXW7 exon 5 whichencodes F-box domain of the proteinHeterozygous knock-in of FGFR2 activating mutation(S252W)Heterozygous knock-in of FGFR3 activating mutation(S249C)Heterozygous knock-in of FLT3 activating mutation(D835Y)Horizon Discovery全細胞株リスト123456789FLT3 (ΔI836/+) HD 104-036 HCT116 ColonGLUT1 (SLC2A1)Heterozygous knock-in of FLT3 activating mutation (ΔI836)GLUT1 (-/-) HD R05-011 RKO Colon Homozygous knock-out of GLUT1GLUT1 (-/-) HD R00-024 DLD-1 Colon Homozygous knock-out of GLUT1GNA11GNA11 (Q209L/+) HD 104-052 HCT116 ColonGNAQGNAQ (Q209L/+) HD 104-045 HCT116 ColonGNASGNAS (R201C/+) HD 103-040 SW48 ColonH-Ras(HRAS)HRAS (G12V/+) HD 103-034 SW48 ColonHAUSP (USP7)Heterozygous knock-in of GNA11 activating mutation(Q209L)Heterozygous knock-in of GNAQ activating mutation(Q209L)Heterozygous knock-in of GNAS activating mutationR201CHeterozygous knock-in of HRAS activating mutation(G12V)USP7 (-/-) HD R02-028 HCT116 Colon Homozygous knock-out of USP7HAUSP (USP7)USP7 (-/-) HD 115-028 DLD-1 Colon Homozygous knock-out of USP7USP7 (+/-) HD R02-029 HCT116 Colon Heterozygous knock-out of USP7HSF1HSF1 (+/+/-) HD R12-008 HCT116 Colon Knock-out of one HSF1 allele in triploid parental cellsHSPA8HSPA8 (+cKO/-) HD 104-058 HCT116 ColonKnock-out of allele 1 of HSPA8. Conditional knockoutof allele 2 by introduction of re-recombinase.AvailableIsogenic Cell LinesIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsAvailableX-MAN ? HaloTag RReporter Kits51