ブックタイトル2013ATCC

概要

2013ATCC

遺伝子名カタログNo.親株名組織特記事項KRAS (G12V/+) HD 103-007 SW48 ColonKRAS (G12V/+); PIK3CA (E545K/+) HD 201-002 MCF10A BreastKRAS (G13D/-) HD 104-011 HCT116 ColonKRAS (G13D/-) HD 105-011 DLD-1 ColonKRAS (G13D/+) HD 116-009 LIM1215Colon(ascending)KRAS (G13D/+) HD 100-004 hTERT-HME1 BreastKRAS (G13D/+) HD 103-002 SW48 ColonKRAS (G13D/+); PIK3CA (H1047R/+) HD 200-003 hTERT-HME1 BreastHeterozygous knock-in of KRAS activating mutation(G12V)Double heterozygous knock-in of KRAS and PIK3CAactivating mutationsKnock-out of wild type KRAS allele in heterozygousparental cellsKnock-out of wild type KRAS allele in heterozygousparental cellsHeterozygous knock-in of KRAS activating mutation(G13D)Heterozygous knock-in of KRAS activating mutation(G13D)Heterozygous knock-in of KRAS activating mutation(G13D)Double heterozygous knock-in of KRAS and PIK3CAactivating mutationsHorizon Discovery全細胞株リスト123456789KRAS (G12V/+); PIK3CA (H1047R/+)HD 201-003MCF10ABreastKRAS (G12V/+); TP53 (-/-)HD 101-027MCF10ABreastKaiso (ZBTB33)ZBTB33 (-/Y)HD 115-034HCT116ColonDouble heterozygous knock-in of KRAS and PIK3CAactivating mutationsHomozygous knock-out of TP53; heterozygousknockin of KRAS activating mutation (G12V)Knock-out of X-linked ZBTB33 allele in male parentalcellsAvailableIsogenic Cell LinesKDM5AKDM5A (+/-) HD 104-053 HCT116 Colon Heterozygous knock-out of KDM5AKDM5CKDM5C (-/Y) HD 104-063 HCT116 Colon Heterozygous knock-out of KDM5CKITKIT (D816V/+) HD 104-026 HCT116 ColonKu70 (XRCC6)XRCC6 (+/-); LIG4 (-/-) HD R02-064 HCT116 ColonXRCC6 (+/-); PRKDC (-/-) HD R02-051 HCT116 ColonHeterozygous knock-in of KIT activating mutation(D816V)Heterozygous knock-out of XRCC6; Homozygousknock-out of LIG4Homozygous knock-out of PRKDC; heterozygousknock-out of XRCC6XRCC6 (+/-) HD R02-053 HCT116 Colon Heterozygous knock-out of XRCC6XRCC6 (+/-) HD R08-002 NALM-6 B-Cell Heterozygous knock-out of XRCC6Ku86 (XRCC5)XRCC5 (+/-) HD 115-097 HCT116 Colon Heterozygous knock-out of XRCC5XRCC5 (+/-) HD 115-102 NALM-6 B-Cell Heterozygous knock-out of XRCC5XRCC5 (+/-); TP53 (-/-) HD 115-101 HCT116 ColonHeterozygous knock-out of XRCC5; homozygousknock-out of TP53In DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsXRCC5 (+floxed/-) HD R02-055 HCT116 ColonXRCC5 (+floxed/-); LIG4 (-/-) HD R02-056 HCT116 ColonKnock-out of single XRCC5 allele and flanking ofexon 3 in remaining allele with LoxP sitesKnock-out of single XRCC5 allele and flanking of exon3 in remaining allele with LoxP sites; homozygousknock-out of LIG4AvailableX-MAN ? HaloTag RReporter Kits53