ブックタイトル2013ATCC

概要

2013ATCC

123456789Horizon Discovery全細胞株リスト遺伝子名カタログNo.親株名組織特記事項XRCC5 (+floxed/-); LIG4 (-/-) HD R02-057 HCT116 ColonXRCC5 (+floxed/-); RAD54B (+/-/-) HD R02-059 HCT116 ColonXRCC5 (+floxed/+) HD R02-054 HCT116 ColonLIGIII (LIG3)LIG3 (+floxed/-) HD R02-061 HCT116 ColonKnock-out of single XRCC5 allele and flanking of exon3 in remaining allele with LoxP sites; homozygousknock-out of LIG4Knock-out of single XRCC5 allele and flanking ofexon 3 in remaining allele with LoxP sites; doubleknock-out of RAD54B in triploid parental cellsHeterozygous flanking of XRCC5 exon 3 with LoxPsitesKnock-out of one LIG3 allele and flanking of exon 4 inremaining allele with LoxP sitesLIG3 (+floxed/+) HD R02-060 HCT116 Colon Heterozygous flanking of LIG3 exon 4 with LoxP sitesLIGIV (LIG4)LIG4 (-/-) HD R02-063 HCT116 Colon Homozygous knock-out of LIG4AvailableIsogenic Cell LinesIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsLIG4 (-/-) HD 115-041 NALM-6 B-Cell Homozygous knock-out of LIG4LIG4 (-/-); RAD54B (+/-/-) HD R02-066 HCT116 ColonLIG4 (-/-); RAD54B (+/+/-) HD R02-065 HCT116 ColonLIG4 (-/-); XRCC6 (+/-) HD R02-064 HCT116 ColonHomozygous knock-out of LIG4; double knock-outof RAD54B in triploid parental cellsHomozygous knock-out of LIG4; single knock-out ofRAD54B in triploid parental cellsHeterozygous knock-out of XRCC6; Homozygousknock-out of LIG4LIG4 (+/-) HD R02-062 HCT116 Colon Heterozygous knock-out of LIG4LIG4 (-/-); XRCC5 (+floxed/-) HD R02-056 HCT116 ColonLIG4 (-/-); XRCC5 (+floxed/-) HD R02-057 HCT116 ColonMCTS1MCTS1 (-/Y) HD 115-094 HCT116 ColonMEK1 (MAP2K1)Knock-out of single XRCC5 allele and flanking of exon3 in remaining allele with LoxP sites; homozygousknock-out of LIG4Knock-out of single XRCC5 allele and flanking of exon3 in remaining allele with LoxP sites; homozygousknock-out of LIG4Knock-out of X-linked MCTS1 allele in male parentalcellsMAP2K1 (-/-) HD R02-030 HCT116 Colon Homozygous knock-out of MAP2K1MAP2K1 (-/-) HD R05-010 RKO Colon Homozygous knock-out of MAP2K1MAP2K1 (-/-) HD R07-001 VACO 432 Colon Homozygous knock-out of MAP2K1MAP2K1 (-/-) HD R00-017 DLD-1 Colon Homozygous knock-out of MAP2K1MAP2K1 (P124L/+) HD 104-034 HCT116 ColonMEK2 (MAP2K2)Heterozygous knock-in of MAP2K1 activatingmutation (P124L) conferring drug resistanceMAP2K2 (-/-) HD R02-031 HCT116 Colon Homozygous knock-out of MAP2K2AvailableX-MAN ? HaloTag RReporter KitsMAP2K2 (-/-) HD R05-007 RKO Colon Homozygous knock-out of MAP2K2MAP2K2 (-/-) HD R07-002 VACO 432 Colon Homozygous knock-out of MAP2K2MAP2K2 (-/-) HD R00-018 DLD-1 Colon Homozygous knock-out of MAP2K254