ブックタイトル2013ATCC

概要

2013ATCC

遺伝子名カタログNo.親株名組織特記事項TP53 (-/-) HD 115-049 NALM-6 B-Cell Homozygous knock-out of TP53TP53 (-/-) HD 101-005 MCF10A Breast Homozygous knock-out of TP53TP53 (-/-) HD 103-004 SW48 Colon Homozygous knock-out of TP53TP53 (-/-); BRAF (V600E/+) HD 101-024 MCF10A BreastTP53 (-/-); BRAF (V600K/+) HD 101-025 MCF10A BreastTP53 (-/-); EGFR (ΔE746-A750/+) HD 101-029 MCF10A BreastTP53 (-/-); KRAS (G12V/+) HD 101-027 MCF10A BreastHomozygous knock-out of TP53; heterozygousknockin of BRAF activating mutation (V600E)Homozygous knock-out of TP53; heterozygousknockin of BRAF activating mutation (V600K)Homozygous knock-out of TP53; heterozygousknockin of EGFR activating mutation (ΔE746-A750/+)Homozygous knock-out of TP53; heterozygousknockin of KRAS activating mutation (G12V)TP53 (+/-) HD R02-037 HCT116 Colon Heterozygous knock-out of TP53Horizon Discovery全細胞株リスト123456789TP53 (+/-) HD R05-009 RKO Colon Heterozygous knock-out of TP53TP53 (+/-) HD R06-001 SW48 Colon Heterozygous knock-out of TP53TP53 (+/-) HD 115-048 NALM-6 B-Cell Heterozygous knock-out of TP53TP53 (+/sil) HD 105-005 DLD-1 ColonTP53 (R248W/-) HD 104-003 HCT116 ColonHeterozygous knock-in of wild type TP53; secondallele silencedKnock-in of mutant (R248W) TP53 and knock-out ofwild type alleleTP53 (R248W/+) HD 104-002 HCT116 Colon Heterozygous knock-in of mutant (R248W) TP53TP53 (R273H/+) HD 103-008 SW48 Colon Heterozygous knock-in of mutant (R273H) TP53TP53 (S241F/-) HD 105-014 DLD-1 Colon Knock-out of silenced TP53 alleleTP53 (sil/-) HD 105-004 DLD-1 ColonTP53 (-/-); XRCC5 (+/-) HD 115-101 HCT116 ColonTP53 (-/-); PIK3CA (H1047R/+) HD 101-043 MCF10A BreastPDGFRAPDGFRA (D842V/+) HD 104-064 HCT116 ColonPDPK1Heterozygous knock-out of TP53 mutant (S241F)allele; second allele silencedHeterozygous knock-out of XRCC5; homozygousknock-out of TP53Heterozygous knock-in of PIK3CA kinase domainactivating mutation in TP53 (-/-) parental cell lineHeterozygous knock-in of PDGFRA activatingmutation (D842V)PDPK1 (-/-) HD R00-028 DLD-1 Colon Homozygous knock-out of PDPK1PDPK1 (+/-) HD R02-080 HCT116 Colon Heterozygous knock-out of PDPK1PI3Kα(PIK3CA)PIK3CA (H1047R/+);EGFR (ΔE746-A750/+)PIK3CA (H1047R/+);EGFR (ΔE746-A750/+)HD 200-001 hTERT-HME1 BreastHD 201-001 MCF10A BreastPIK3CA (E545K/+); KRAS (G12V/+) HD 201-002 MCF10A BreastPIK3CA (H1047R/+); KRAS (G13D/+) HD 200-003 hTERT-HME1 BreastDouble heterozygous knock-in of EGFR and PIK3CAactivating mutationsDouble heterozygous knock-in of EGFR and PIK3CAactivating mutationsDouble heterozygous knock-in of KRAS and PIK3CAactivating mutationsDouble heterozygous knock-in of KRAS and PIK3CAactivating mutationsAvailableIsogenic Cell LinesIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsAvailableX-MAN ? HaloTag RReporter Kits57