ブックタイトル2013ATCC

概要

2013ATCC

遺伝子名カタログNo.親株名組織特記事項RAC1 (Q61L/+/+) HD 103-014 SW48 Colon Heterozygous knock-in of RAC1 mutant (Q61L)RAD54BRAD54B (+/-/-); LIG4 (-/-) HD R02-066 HCT116 ColonRAD54B (+/+/-); LIG4 (-/-) HD R02-065 HCT116 ColonRAD54B (+/-/-); XRCC5 (+floxed/-) HD R02-059 HCT116 ColonRB1RB1 (+/-) HD 102-005 hTERT RPE-1 RetinapigmentepitheliumS100A4Homozygous knock-out of LIG4; double knock-outof RAD54B in triploid parental cellsHomozygous knock-out of LIG4; single knock-out ofRAD54B in triploid parental cellsKnock-out of single XRCC5 allele and flanking ofexon 3 in remaining allele with LoxP sites; doubleknock-out of RAD54B in triploid parental cellsHeterozygous knock-out of RB1Horizon Discovery全細胞株リスト123456789S100A4 (-/-) HD 115-096 HCT116 Colon Homozygous knock-out of S100A4Securin (PTTG1)PTTG1 (-/-) HD R02-043 HCT116 Colon Homozygous knock-out of PTTG1SETD2SETD2 (R1492*/+) HD 104-068 HCT116 ColonSMAC (DIABLO)Heterozygous knock-out of SETD2 by knock-in ofpremature stop codon (R1492*)DIABLO (-/-) HD R02-045 HCT116 Colon Homozygous knock-out of DIABLOSMAD4SMAD4 (-/-) HD 104-005 HCT116 Colon Homozygous knock-out of SMAD4STAT3STAT3 (-/-) HD 115-017 DLD-1 Colon Homozygous knock-out of STAT3AvailableIsogenic Cell LinesIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesSTAT3 (Y705F/Y705F) HD 115-016 DLD-1 Colon Homozygous knock-in of STAT3 Y705F mutationTOP2β(TOP2B)TOP2B (-/-) HD 115-061 NALM-6 B-Cell Homozygous knock-out of TOP2BXIAPXIAP (-/Y) HD R02-047 HCT116 ColonXIAP (-/Y) HD R00-023 DLD-1 ColonXLF (NHEJ1)Knock-out of X-linked XIAP allele in male parentalcellsKnock-out of X-linked XIAP allele in male parentalcellsNHEJ1 (-/-) HD R02-068 HCT116 Colon Homozygous knock-out of XLFNHEJ1 (-/-);NHEJ1 (L115A) cDNA overexpressionNHEJ1 (-/-);NHEJ1 (L179A) cDNA overexpressionHD R02-070 HCT116 ColonHD R02-071 HCT116 ColonHomozygous knock-out of XLF with overexpressionof mutant (L115A) XLFHomozygous knock-out of XLF with overexpressionof mutant (L179A) XLFIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsAvailableX-MAN ? HaloTag RReporter Kits59