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2013ATCC

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2013ATCC

EGFR遺伝子名カタログNo.親株名組織特記事項EGFR (I491M/+/+) HD 103-043 SW48 ColonFANCBFANCB (-/Y) HD 115-065 NALM-6 B-CellFANCB (-/Y); MUS81 (-/-) HD 115-092 NALM-6 B-CellFANCCFANCC (+/+/-) HD R05-003 RKO ColonHPRT (HPRT1)HPRT (-/Y) HD R02-052 HCT116 ColonHeterozygous knock-in of EGFR I491M mutation intrans configuration with endogneous G719S mutationKnock-out of X-linked FANCB allele in male parentalcellsKnock-out of X-linked FANCB allele in male parentalcells; homozygous knock-out of MUS81Knock-out of single FANCC allele in triploid parentalcellsKnock-out of X-linked HPRT allele in male parentalcellsHorizon Discovery全細胞株リスト123456789HPRT (-/Y) HD 115-064 NALM-6 B-CellKu70 (XRCC6)Knock-out of X-linked HPRT allele in male parentalcellsXRCC6 (+/-) HD 115-068 NALM-6 B-Cell Heterozygous knock-out of XRCC6Ku86 (XRCC5)XRCC5 (+/-) + XRCC5 cDNA HD 115-099 HCT116 ColonXRCC5 (+floxed/-); RAD54B (+/-/-) HD R02-058 HCT116 ColonLIGI (LIG1)Heterozygous knock-out of endogenous XRCC5 withoverexpression of wild type XRCC5Knock-out of single XRCC5 allele and flanking ofexon 3 in remaining allele with LoxP sites; doubleknock-out of RAD54B in triploid parental cellsLIG1 (+/-) HD 115-066 NALM-6 B-Cell Heterozygous knock-out of LIG1LIGIV (LIG4)LIG4 (-/-); BLM (-/-) HD 115-079 NALM-6 B-Cell Double homozygous knock-out of BLM and LIG4LIG4 (-/-); BLM (+/-) HD 115-078 NALM-6 B-CellLIG4 (-/-); TDP1 (+/-) HD 115-086 NALM-6 B-CellHeterozygous knock-out of BLM; homozygous knockout of LIG4Homozygous knock-out of LIG4; heterozygousknock-out of TDP1LIG4 (-/-); TOP2B (-/-) HD 115-089 NALM-6 B-Cell Double homozygous knock-out of LIG4 and TOP2BLIG4 (-/-); TOP2B (+/-) HD 115-088 NALM-6 B-CellHomozygous knock-out of LIG4; heterozygousknock-out of TOP2BLIG4 (+/-) HD 115-040 NALM-6 B-Cell Heterozygous knock-out of LIG4METMET (Δexon16/Δexon16) HD 115-093 DLD-1 ColonMUS81MUS81 (-/-); FANCB (-/Y) HD 115-092 NALM-6 B-CellHomozygous double knockout of exon 16 in METresulting in a kinase dead receptor.Knock-out of X-linked FANCB allele in male parentalcells; homozygous knock-out of MUS81MUS81 (+/-) HD 115-054 NALM-6 B-Cell Heterozygous knock-out of MUS81AvailableIsogenic Cell LinesIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsAvailableX-MAN ? HaloTag RReporter Kits61