ブックタイトル2013ATCC
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2013ATCC
123456789Horizon Discovery全細胞株リストp21 (CDKN1A)遺伝子名カタログNo.親株名組織特記事項CDKN1A (+/-) HD R02-036 HCT116 Colon Heterozygous knock-out of CDKN1Ap53 (TP53)TP53 (S241F/sil); CHEK1 (+/-) HD R00-027 DLD-1 ColonHeterozygous knock-out of CHEK1; TP53 (S241F)mutant backgroundTP53 (-/-); BLM (-/-) HD 115-091 NALM-6 B-Cell Double homozygous knock-out of BLM and TP53TP53 (+/-); BLM (-/-) HD 115-090 NALM-6 B-CellPaxillin (PXN)Homozygous knock-out of BLM; heterozygous knockout of TP53PXN (Y88F/Y88F) HD 115-029 DLD-1 Colon Homozygous knock-in of PXN Y88F mutationPXN (Y88F/Y88F) HD 115-030 HCT116 Colon Homozygous knock-in of PXN Y88F mutationAvailableIsogenic Cell LinesIn DevelopmentIsogenic Cell LinesAvailableTagged and ReporterCell LinesIn DevelopmentTagged and ReporterCell LinesAvailableX-MAN ? NanoLuc ?Reporter KitsAvailableX-MAN ? HaloTag RReporter KitsPPARδ(PPARD)PPARD (+/-) HD R02-039 HCT116 Colon Homozygous knock-out of PPARDRAD54BRAD54B (+/-/-); XRCC5 (+floxed/-) HD R02-058 HCT116 ColonS100A4Knock-out of single XRCC5 allele and flanking ofexon 3 in remaining allele with LoxP sites; doubleknock-out of RAD54B in triploid parental cellsS100A4 (+/-) HD 115-095 HCT116 Colon Heterozygous knock-out of S100A4Securin (PTTG1)PTTG1 (+/-) HD R02-044 HCT116 Colon Heterozygous knock-out of PTTG1SMAD4SMAD4 (+/-) HD R02-046 HCT116 Colon Heterozygous knock-out of SMAD4STAT3STAT3 (Y705F/Y705F) HD 115-019 RKO Colon Homozygous knock-in of STAT3 Y705F mutationTDP1TDP1 (+/-); LIG4 (-/-) HD 115-086 NALM-6 B-CellHomozygous knock-out of LIG4; heterozygousknock-out of TDP1TDP1 (+/-) HD 115-056 NALM-6 B-Cell Heterozygous knock-out of TDP1TOP1TOP1 (+/-) HD 115-072 NALM-6 B-Cell Heterozygous knock-out of TOP1TOP2α(TOP2A)TOP2A (+/-) HD 115-071 NALM-6 B-Cell Heterozygous knock-out of TOP2ATOP2β(TOP2B)TOP2B (-/-); LIG4 (-/-) HD 115-089 NALM-6 B-Cell Double homozygous knock-out of LIG4 and TOP2B62